英语翻译Germline PTEN mutations are present in approximately 80% of patients with Cowden syndrome .This disease,which is also known as multiple hamartoma syndrome,is a familial syndrome that includes diverse types of cancer conditions including e

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英语翻译Germline PTEN mutations are present in approximately 80% of patients with Cowden syndrome .This disease,which is also known as multiple hamartoma syndrome,is a familial syndrome that includes diverse types of cancer conditions including e
英语翻译
Germline PTEN mutations are present in
approximately 80% of patients with Cowden syndrome
.This disease,which is also known as multiple
hamartoma syndrome,is a familial syndrome that includes
diverse types of cancer conditions including early onset
breast cancer.Mutations have been reported to occur at
PTEN in breast cancer in varying frequencies (5-21%)
.Loss of heterozygosity (LOH) is probably
more common (30%) .Mutations at certain residues
of PTEN,that are associated with Cowden’s disease,
affect the ubiquitination of PTEN and prevent nuclear
translocation.These mutations leave the phosphatase
activity intact .Inhibition of PTEN activity leads to
centromere breakage and chromosome instability.
Thus PTEN has diverse activities.

英语翻译Germline PTEN mutations are present in approximately 80% of patients with Cowden syndrome .This disease,which is also known as multiple hamartoma syndrome,is a familial syndrome that includes diverse types of cancer conditions including e
种系PTEN基因突变存在于约80%的错构瘤综合征病人身上.这种病也是一种多元化的综合病,是一种遗传综合病,它能诱发多种恶性肿瘤,例如早期病发的乳腺癌,.这种基因突变发生导致的乳腺癌发生概率有不同程度的变化(5-21%).诱发的杂合性缺失(LOH)也较为普遍.PTEN剩余物的基因突变与考登氏病有关联,它影响PTEN的蛋白化作用并且阻止细胞核的运输作用.这种突变影响不了磷酸酶的活动.抑制PTEN活动课导致着丝点的破损,和染色体的不稳定.所以PTEN有各种各样的不稳定性.

英语翻译Germline PTEN mutations are present in approximately 80% of patients with Cowden syndrome .This disease,which is also known as multiple hamartoma syndrome,is a familial syndrome that includes diverse types of cancer conditions including e PTEN基因英语翻译RNA recognition by the embryonic cell fatedeterminant and germline totipotency factor MEX-3Renewal of totipotent stem cells in the germline and cellular differentiation during early embryogenesis rely upon posttranscriptional regulatory m 英语翻译ALO YAH XI MU SIZ还有BA MU YA 求PTEN基因的序列谁知道 PTEN的序列啊? 英语翻译Human colon cancer cell lines HCT116 and SW480 were transfected with phosphatase and tensin homolog deleted on chromosome 10 (PTEN) siRNA or non-targeting control (NTC). 英语翻译[da:ns] [pæl][lesn] [mu:n] 英语翻译No.60 Mu.1 Tungtor Huayod Trang 92130Thailand 英语翻译请问维语TIXLIK MU YA翻译为汉语英语翻译Application of this technology to engineergenes in rats has not previously been possible because of theabsence of germline-competent ES cells in this species.这句话怎么翻译?注：ES cells 为胚胎干细胞英语翻译DI HATIKU TETAP MERINDUI MU,WALAUPUN KITA TAK BERTEMU,NAMUN DI HATIKU MASIH PILU,KERANA AKU MENCINTAI MU~ 英语翻译When PTEN is mutated,Akt signals via the NF-kappaB/I-kappaB pathway to induce COX-2 expression in endometrial cancer cells.COX-2 can inhibit apoptosis,increase angiogenesis,and promote invasiveness.COX-2 also promotes inflammation/immunos 泰语mu MU BA 英语翻译The assay is based on the enzymatic cleavage of the belowdetailedmethylumbelliferone (MU) coupled substrates and the subsequentdetection of MU released during incubation. 英语翻译Terimakasih sudah menerimaku menjadi teman d fb mu.:-)Kamu bisa berbhasa indondsia?;-)Senang berkenalan denganmu 英语翻译Wann man doch jung ware,sollte er zu der Ferne gehen.(Danke,Herr Mu.) 英语翻译英文翻译：Dear lf you want to succeed you mu st be more dilg